| Tamil Nadu Public Service Commission (TNPSC) Syllabus
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Environmental Toxicology - (Code - 047) |
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Paper - ISection A- Molecular Pharmacology
- Drug Receptors
- Chemical Bonds
- Drugs And Enzymes
- Structure Activity Relationship
- Cellular Pharmacology
- Biological Membrane And Transport Accross Membranes
- Drug Effect On Extra Cellular. Tissue Ingredients.
- Integral Pharmacology
- Pharmacokinetics
- Principal Effects Of Drugs
- Side Effects Of Drugs
- Complex Drug Actions - Commulation, Tolerence, Synergism, Antagonism, Potentiation.
- Pharmacogenetics
- Drug Selectivity
- Chemotheraphy
- General Principles Of Chemotheropy
- Chemotherapy Of Infectious Diseases
- Chemotherapy Of Malignancy
- Quantative Aspects In Pharmacology
- Dose Response Relationship
- Bioassay
- Chemical Assay
- Radio Immuno Assay
- Drug Standardization
- Pharmacological Screening Of Siddha Medicinal Preparations
- Selection Of Plants, Minerals And Animal Products Used In Siddha Medicine
- Extraction,Preparation And Screening Of Pharmacologically Active Principles In Various Experimental Models.
- Biostatistics
Centering Constants; Means, MedianAndMode, Variability Constants - Average, Range,Interquartile Range, Average Deviation, Standard Deviation; Tests Of Significance Student'sTest, Chi Square Test, Anova, Application Of Statistics In Evaluation Of Siddha And Herbal Preparations And Formulations.
Top Section B - General Principles Of Toxicology - Introduction To Toxicology - Toxicology - Definition And Branches - Classification Of Toxic Agents.
- Toxins - Acute And Chronic Exposure - Route, Site, Duration And Frequency Of Exposure.
- Spectrum Of Toxic Effects - Allergic And Idiosyncratic Reactions; Toxicity; Immediate And Delayed; Reversible And Irreversible; Local Systemic And Selective.
- Toxicokinetics - Abserption, Distribution, Metabolism And Excretion And Influencing Factors.
- Dose - Response Relationship - Ld 50, Ed 50
- Mechanism Of Action.
- Chemical - Chemical Interaction, Chemical - Diet Interation - Potentiation, Synergism And Antagonism.
- Factors Influencing Toxicity - Factors Related To The Agent, Exposure Situation And Internal Environment Of The Subject, External Enviornmental Factors.
- ToxicityTestsInAnimals-Acute,Subacute And ChronicTests Mutagenicity,Teratogenicity And 0.Carcinogenicity Tests, Interpretation Of Laboratory Data.
- Treatment And Management Of Poisoning - Antidotal Principles And Their Application.
Top Section C - Instrumentation- Thin Layer Chromatography & Paper Electrophoresis
- U.V. - Vis Spectro Photometry - Differential Spectrophotometry
- Infra-Red Spectrophotometry - Interpretation Of Spectra.
- NMR Spectorphotometry And Its Applications.
- Mass Spectrometry As Applied To Drugs Analysis
- Gaschromatography & G C - Ms Techniques.
- Atomic Absorption Spectrophotometry And Neutron Activation
- Analysis As Applied To Elemental Analysis.
- X-Ray Diffraction In Toxicological Analysis
- High Performance Liquid Chromatography In Toxicology
- Radio Immuno Assay In Analysis Of Body Fluids For Poisons.
Top Paper - IISection A- Drugs Acting On Various Systems
- Cns
- Ans
- Respiratory
- Cardio Vasular
- Gastrointestinal
- Genito Urinary
- Musculo Skeletal
- Reproductive Pharmacology
- Drugs Acting On The Male & Female Reproductive System
- Antifertility Agents
- Hormone Replacement Therapy
- Hormones And Hormone Antagonists
- Endocrinological Disorders And Drug Treatment
- Anti Diabetic Drugs
- Anti Thyroid Drugs
- Hormone Replacement Therapy in Endocrinological Disorders
- Vitamins, Minerals And Nutritional Supplements
- Deficiencies And their Drug Treatment.
- Analgesic, Anti Pyretic And Antinflammartory Drugs - Drugs Used In Inflammatory Disorders - Anti Artheritic, Gout Drugs.
- Chemotherapy - General Principles - Chemotherapy Of Infectious Diseases, Chemotherapy Of Malignancy.
Top Section B- Preliminaries - Central & Peripherac Nervous Systems Neuro Transmitters
- Drug Addiction & Habituation
- Drug Dependence
- Social & Personality Factors Conductive To Drug Dependence
- Dependence Potential And Dependence Liability
- Narcotic Analgesies
- Cannabis And Cannabenoids
- Psychotogenic Drugs.
- Amphetamines.
- Cocaine And Erythroxylon Coca
- Mono Amine Oxidase Inhibitors - Triexelic Antidepressants
- Xanthine Beverages And Xanthine Alkaloids
- Abuse Of & Toxicity Associated With Hypnotics And Seditives.
- Barbiturates
- Benzodiazepines
- Miscellaneous
- (i) Acute & Chronic Toxicity Associated With Abeottol Abuse
(ii) Toxicity & Treatment Associated With Methanol Poisioning - Abuse Of Inhalants & Glue Sniffing.
- Tobacco Smoking - Tobacco Use - Toxicity & Complications Associated With
- Treatment & Prevention Of Drug Addiction.
- Siddha & Other Methods Associated With The Treatment & Prevention Of Drug Addiction
- Siddha Drugs In Preventing & Treating Drug Toxicity Associated With Liver And Other Organs.
- Experimental Techniques In Evaluating The Addiction Potential And Liability Of A Drug.
Top Section C - Forensic Toxicology - Poisons Acts And Type Of Poisoning In India.
- Mode Of Action of Poisons.
- Causes Which Modify The Effects
- Corrosive Poisons
- Metals And Their Salts And Methods Of Estimation
- Volatile Poisons - Mode Of Action And Analysis
- Insecticides
- Synthetic Drugs
- Plant Poisons And Animal Poisons-Isolation From Body Fluids.
- Extraction And Purification In Toxicological Analysis.
- Screening Tests For Common Poisons.
- Gas Analysis.
- Glycosides And Alkaloids And Analysis From Biological Fluids
- Barbiturates And Other Synthetic Drugs
- Metabolic Pathways Of Poisons
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